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How To Train For a Marathon: The Complete Guide

11th November 2025

11th November 2025

By Josh Makin

The marathon - the magnum opus when it comes to being a runner, (and a feature of so many bucket lists). Something that seems so impossible, yet so many make possible.

Preparing for a marathon is no small feat. It requires physical stamina, mental resilience, and a well-thought-out strategy. Whether you're a first-time runner or a seasoned athlete, marathon training is a journey that demands consistency, science-backed planning, and smart recovery.

With the largest organised marathons on the horizon (think Dubai, Boston and London), we thought there was no better time to reignite the conversation and discuss just how you can smash your marathon goals, with targeted training, nutrition and perseverance.

This guide explores everything you need to know about training for a marathon, how long it typically takes, and the best practices to follow for optimal performance and recovery.

Right, let’s get into it.

Setting your marathon goals

Before lacing up your trainers and mapping out your training schedule, first you need to understand what you want to achieve with the marathon.

For instance:

  • Are you aiming to complete a marathon for the first time?
  • Perhaps complete in a target time?
  • Shave minutes off a personal best?
  • Simply finish feeling strong and injury-free?

These choices should be driven by your own body and what you think can be achieved - one of the biggest mistakes you can make in running or fitness in general is to try and meet someone else’s goals.

It can be daunting to decide these goals, especially if you are starting the process as a beginner. One rule of thumb that can be useful is to set yourself a series of SMART goals for increased objective definition.

  • Specific: What is it you are looking to achieve? When are you looking to achieve this by? Are you training for a particular event? Have you run 42.2k before? As the name suggests, you should try and make the goal as specific as possible, with all details included. This will help you tailor your training plan.
  • Measurable: Have you defined a measurement for your specific goal? Time related goals might see you tailor your training plan to a particular pace. If you’re normally a half marathon runner and want to build up your measurable fitness to a full marathon, then building up your endurance is key.
  • Achievable: Is your goal attainable in the timeframe you have given yourself? If not, maybe it’s worth giving yourself more time? Or even switching to a half marathon, 5k or 10k instead.
  • Relevant: Are your goals tailored to you? If not, it might be worth a rethink. This also applies to a training plan. Don’t train for a 5k if a marathon distance is the goal.
  • Time-Based: With a full training plan in place, how long will you need to practice and prepare for the marathon? There’s nothing more likely to set you up for failure than cramming 6 months of training into 4 weeks.

Not only can you use these smart goals to inform what it is you want to achieve, but they will also help you to tailor your training plan going forward.

Woman running

Marathon training plan tips

So, you’ve got your SMART goals set and know what you want. Next up, it’s about training and fuelling your body, muscles and mind ready for the big event.

The four phases of marathon training

At the core of effective marathon prep is a structured plan. Most programs divide training into four key phases:

  • Base building
  • Intensity training
  • Peak building
  • Tapering

Shall we start from the top?

Base building

During the initial base building phase, the purpose is to condition the body through steady aerobic runs and gradually increase weekly mileage. This creates the endurance foundation necessary for more intensive work.

Typically, base building consists of low intensity (conversational pace) but high-volume workouts. The time you take on base building greatly depends on where your fitness levels lie and how long you have given yourself to train.

Base building for a marathon has the benefit of:

  • Improving your endurance through cellular adaptations, building the body’s ability to use oxygen effectively, delaying fatigue.
  • Enhancing muscle efficiency when burning fat for fuel by preserving carbohydrate stores - these adaptions help the body to keep going for longer (super important for a long distance run like a marathon).
  • Increasing injury prevention and post run recovery by strengthening and building muscular, tendon and bone resistance.  

Intensity running

Once base fitness is established, the next step is to work on ‘intensity’ based runs. This will see you build anaerobic fitness through high intensity but lower volume runs - generally you want to be hitting around 80% to 90% of your maximum heart rate with these runs.

Tempo runs, hill repeats, fartlek training and interval training are all perfect intensity workouts that challenge your cardiovascular efficiency and improve lactate threshold.

For those looking to hit certain times within the marathon or smash a PB, this training method is for you (although anyone will of course benefit).

Intensity training for a marathon has the benefit of:

  • Improved lactate tolerance, meaning that the body becomes more efficient at fuelling the cells during high intensity workouts. The benefit? You can run harder for longer before experiencing fatiguing effects - read this study for more detail.
  • Increased speed and power when running by building more fast-twitch muscle fibres. This helps to improve running speed - especially useful when going for a PB.
  • Building mental toughness. Pushing yourself now in training will teach you how to work through mental and physical discomfort and ingrain the resilience needed for what will likely be the most challenging run of your life.
treadmill runner

Peak training

The next part of your training plan will consist of something called ‘peak training’.

Generally starting at around 60% through your training journey, this is where you are going to put your endurance and pace building to the test by completing the longest distance runs so far.

Running distances should get longer until you start going for that 30+ km distance (slowly building up of course). For those who have set PB, or pace-related SMART goals, this is also where you are going to practice at a longer distance.

Rather than full long distance, we would suggest initially breaking up your runs into longer intervals to help build up your long-distance pace. We would recommend 10k intervals as an effective tool for marathon pace training.

The important thing here is to make sure you are carefully planning your runs with effective sleep and effective nutrition (see our nutrition tips below). The last thing anyone wants is to go through months of training only to miss out due to injury.

Peak training for a marathon has the benefit of:

  • Building your confidence
  • Simulating the distances of race day. Completing this stage will give you a complete sense of the runners high. The hard work is done, and now you know you can do it!
  • Increasing endurance and stamina, building on the endurance you may not even realise you have built up from base and intensity training.
  • Driving greater fatigue resistance.
  • Gradually building to these longer distance workouts improves lactate tolerance, enhances muscle efficiency and builds the body’s ability to use oxygen effectively.
Group of runners

Tapering

Right, you’ve completed the longest distance prep runs and are ready to go.

So why is there still one phase of training left?

Tapering (while often overlooked) is the final stage of marathon training

It's the stage where you know that the hard training is done and race day is almost here. It occurs around the final 2-3 weeks of training and sees much shorter runs taken at your target marathon pace.

The goal here is to reduce the fatigue you’ve built over the many months of training and ensure you are in the best levels of fitness on the big day. It allows the body to recover and rebuild, ensuring you're rested, primed, and sharp come race day.

While it might sound counterproductive, the science here doesn’t lie. According to a 2007 meta-analysis, tapering your runs can improve performance by up to 3%.

Tapering before a marathon has the benefit of:

  • Replenishing energy stores.
  • Allowing for muscle and tissue repair.
  • Improving aerobic capacity.
  • Boosting confidence through improved mental clarity.

Nutrition and supplementation for endurance for marathon training

With that said, physically and mentally training your body is only one part of the puzzle. You want to be sure that you are fuelling effectively with complete nutrition.

If this blog hasn’t made it obvious, running (especially these sorts of long distances) stresses the body. This makes nutrition your most powerful tool for recovery and performance. A balanced diet rich in carbohydrates, lean protein, and healthy fats can help fuel training and accelerate recovery.

We’ve written a whole blog around nutrition that we would recommend checking out for further info.

Woman drinking protein shake

When weekly mileage begins to build and time becomes scarce (as it does, we all have busy lives), supplementation can also offer a smart, efficient solution. Protein, in particular, is critical for muscle repair, with between 1.4 to 1.6g of protein per kilogram of body weight required per day to support recovery during the training process

A high-quality protein supplement can fill nutritional gaps, support muscle synthesis, and help reduce soreness. Innermost The Strong Protein for instance offers 31g of protein per serving, helping to maximise muscle growth throughout the training process.

Beyond protein, other supplements like electrolytes, adaptogens, and functional nutrients can also play a role in effective marathon nutrition - see our The Hydrate Blend premium sachets, The Rise Capsules and The Reset Capsules for more detail.

For wellness-focused runners and those with holistic health goals, incorporating ingredients like ashwagandha or reishi mushroom (featured in The Rise Blend) can help manage stress and improve recovery outcomes.

For a more in-depth look at science-backed sports nutrition, check out our complete guide to running supplements.

Making the most of marathon gear

Watches and apps

Good news, today’s runner has more tools and tech at their disposal than ever before, each of which can help assist you on your marathon journey.

Wearables such as a Garmin or Apple Watch can be fantastic for tracking mileage, heart rate, and recovery metrics.

Apps like Strava and Runna provide coaching frameworks and social accountability. These platforms offer feedback loops that help refine pacing, identify overtraining risk, and maintain motivation.

Running shoes

Footwear, too, is a crucial factor.

Investing in a new quality pair of running shoes that match your gait and terrain (beyond being one of the most fun investments for a runner) can prevent injuries and improve efficiency.

For long-distance training, rotating between two pairs helps extend the life of your shoes and reduce repetitive strain.

Person tying running shoes

Recovery tools

Recovery tools, including foam rollers, massage guns, and compression gear, support circulation and muscle repair.

Many science-focused runners also find value in tracking sleep quality and using devices that measure HRV (heart rate variability), offering deeper insight into readiness levels.

What to do on marathon day?

After months of training, it’s finally coming up to marathon day. In many ways, it can feel overwhelming. You’ve done all the hard work and, now it’s simply a waiting game

Or so it seems...

Below we have included our top tips on how to prepare for marathon day, starting from the day before and leading to post run recovery. Shall we jump into it?

The night before the marathon

The night before race day is all about setting yourself up for success.

You’ve done the training - now it’s time to prepare mentally and physically for the big effort ahead.

Eat well, but don’t overdo it. A familiar meal rich in complex carbohydrates (like pasta, rice, or potatoes) with a moderate amount of protein and low fibre is ideal. Avoid anything new or spicy that could upset your stomach.

Hydrate smart. Drink water steadily throughout the day, but don’t overload at night. Add electrolytes if temperatures will be high or if you’ve been training in the heat.

Organisation is also really important for peace of mind (and to avoid any last-minute panics on the day. Lay out your gear. Double-check that everything is ready: bib number, shoes, socks, GPS watch, any supplements, and clothes.

Last up, try and get to bed early but equally, don’t worry if you can’t sleep. It’s normal to feel nervous. A poor night of sleep before a race won’t ruin your performance, especially if you’ve banked good rest earlier in the week and have done all the training to prepare.

Marathon day

When marathon day finally arrives it’s fairly normal to feel an overwhelming mix of nerves and excitement. In the morning, we would recommend a high carb meal around 2-3 hours in advance to maximise glycogen stores and ensure a good amount of digestion time (avoid anything high in fibre that could drive digestive issues).

Below we have included a few other key hacks and tips to best prepare you on race day:

  • Arrive early - no-one wants the added pressure of arriving late. Best remedy? Arrive in good time on race day, even if that means waking up an hour or 2 earlier.
  • Stick to what you know - marathon day is not the day to be trying out new things. Don’t go testing new running shoes, gear or supplementation on race day.
  • Don’t start too fast - As I’m sure you’ve worked out over the many months of training, starting out too fast is a recipe for disaster. Try not to get carried way by the initial adrenaline at the start line and stick to the pace you have set yourself.
  • Use water stations wisely - Water stations are there for a reason, but equally (depending on the marathon) they will be well spread out across the track. Try to tailor water sips from your own bottle around where these stations are placed to maximise your hydration intake.
  • Keep mental check-ins - We cannot stress how much of a mental game running can be. Try not to keep checking your watch (if you have one) or fixating on distance/pace - this can lead to increased mental fatigue.

Remember, you have trained for this, and you can do it!

Woman celebrating after running

Post-Race Recovery 

Congratulations! You’ve done it! You’ve completed a marathon and entered an elite group of sportspeople!

Now’s the final stage and one that could make or break how you feel over the next few days/weeks. Recovery. Your body will have been pushed to its limit, so what you do next matters.

  • Keep moving - It will feel oh so tempting to collapse on the ground in exhaustion and celebration - before you do so, try walking for 10-15 minutes after finishing to keep blood flowing and prevent cramping.
  • Refuel quickly - Aim for a snack or shake with a 3:1 ratio of carbs to protein within 30 minutes. While most organised marathons will provide a finishers bag with snacks to enjoy, The Recover Capsules are your secret weapon here.
  • Hydrate and rest - Rehydrate slowly over the next few hours and take it easy for the rest of the day. Elevate your legs and focus on gentle mobility. Post marathon, you should give a full week of rest before resuming any form of structured training. Low impact activities like walking (those who live in Dubai, why not join one of our Walk Club group sessions?), swimming, or yoga are very beneficial here.
  • Reflect and celebrate - This goes without saying, but you’ve completed a marathon! Take time to celebrate your experience and appreciate the accomplishment with friends and family.

Time to get marathon ready

So, there we have it!

Training for a marathon is a transformational experience. It requires structure, self-awareness, and smart choices about how you train, fuel, and recover. We’re hoping that if nothing else, this blog has conveyed that anyone can achieve a marathon distance target - whether starting as a beginner or aiming to get a PB.

For added insight and performance, why not explore our collection of Innermost protein powders, tailored to fit a variety of lifestyles and training needs.

Remember, train smart. Recover well. Run far.

Frequently asked questions

What time should I aim to achieve with a marathon?

While you should always try and tailor your marathon target to your individual goals and body, below are a handful of time brackets depending on whether you are new to running or a seasoned jogger.

  • For beginners: Your goal may be to simply finish the race within the cut-off time (typically around 6 to 7 hours). For many new runners, a finish time between 4:30 and 5:30 hours is realistic with consistent training.
  • For intermediate runners: Those who have completed a race before may aim for a sub-4-hour finish. This requires maintaining a pace of approximately 5:41/km (9:09/mile).
  • For experienced runners: More advanced runners often set aggressive goals, like breaking 3:30 or even 3:00. These targets require disciplined pacing and advanced training strategies.

It’s important to match your goals with your lifestyle, current fitness, and time commitment. Setting realistic, progressive goals ensures long-term motivation and helps avoid burnout or injury.

What’s the right timeframe to begin marathon training?

Another common question for runners is ‘how long will it take to train for a marathon?’

While the exact answer can vary wildly based on both the capacity you yourself have (not to mention the number of weeks/months before race day) and your prior running experience, for those aiming to build a sustainable fitness base, you ideally want to look at a six-month (24-week) plan.

This provides ample time for optimal progression without rushing the 4 training stages mentioned in this article.

Months 1-2: Base Building

  • Focus on consistency through base building training
  • Aim for 3-4 runs per week at conversational pace
  • Gradually increase weekly mileage (start with 15-25km)
  • Introduce intensity runs
  • Include one cross-training or active recovery day

Months 3-4: Building Strength & Endurance

  • Increase mileage to 30-50km per week
  • Continue intensity runs
  • Introduce peak long runs that build up to 20-26km
  • Begin fuelling practice during long runs (supplements, hydration)

Months 5-6: Peak and Taper

  • Peak weekly mileage 50-65km
  • Longest run: 30-35km, 3-4 weeks before race day
  • Tapering starts 2-3 weeks out, reducing mileage by 20-30%
  • Maintain intensity, reduce volume

Each phase should prioritise injury prevention through mobility work, strength training, and recovery protocols.

References

  1. Bosquet, L. et al. (2007). Effect of tapering on performance: a meta-analysis. Medicine & Science in Sports & Exercise, 39 (8), 1358 -1365. Click here.
  2. Hughes, D., Ellefsen, S., and Baar, K. (2018). Adaptations to Endurance and Strength Training. Cold Spring Harb Perspect Med, 8 (6). Click here.
  3. Xie, H., Mao, X., and Wang, Z. (2024). Effect of high-intensity interval training and moderate-intensity continuous training on blood lactate clearance after high-intensity test in adult men. Frontiers in Psychology, 39 (8). Click here.
  4. Jager, R. et al. (2017). International Society of Sports Nutrition Position Stand: protein and exercise. J Int Soc Sports Nutr. Click here.
  5. Jiménez-Alfageme, R. et al. (2025). Nutritional Intake and Timing of Marathon Runners: Influence of Athlete’s Characteristics and Fueling Practices on Finishing Time. Sports Med Open. Click here.
  6. Burke, L. Hawley, J. et al. (2011) Carbohydrates for training and competition. Journal of Sports Sciences. 29. Click here.
  7. DeAngelis, J. (2024) Target Heart Rate Zones: Safely Maximize Your Workouts, Brown Health. Click here.

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The strongest evidence supports gradual improvements in skin hydration and elasticity with daily marine collagen use over roughly 8 to 12 weeks. Evidence for hair, nails and joint support is more limited, so these benefits should be seen as promising but less established than the skin-related research. Marine collagen peptides are broken into smaller fragments, which research suggests are well absorbed into the body. Neither marine nor bovine collagen is automatically better; the right choice depends on your goals, diet and product quality. What is marine collagen? Marine collagen is simply collagen that is sourced from fish - usually the skin and scales that would otherwise be discarded. You can get some collagen from marine foods, although it is usually most concentrated in the skin, bones and connective tissues rather than the fillet itself. 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Marine collagen vs bovine collagen Marine and bovine collagen are two of the most common forms of collagen supplements that you will hear about: Marine collagen is sourced from fish, usually the skin and scales Bovine collagen comes from cattle, most often the hide. Both are commonly hydrolysed into collagen peptides, which means they have been broken down into smaller fragments that are easier for the body to digest and use. The main difference is usually the collagen profile. Marine collagen is typically rich in Type I collagen, the type most strongly associated with skin, bones and connective tissue. Bovine collagen usually contains both Type I and Type III collagen, giving it a slightly broader collagen profile. That does not make one automatically better than the other. Marine collagen may be more appealing if your focus is skin support or you prefer a fish-derived source, while bovine collagen may suit those looking for a wider mix of collagen types. 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Feature Marine collagen Bovine collagen Source Fish or other marine sources, often skin, scales or bones Cattle, usually hides or bones Common collagen types Mainly Type I collagen Type I and Type III collagen Often chosen for Skin hydration, elasticity and beauty-focused routines General collagen support, including skin and connective tissue Digestibility Usually hydrolysed into collagen peptides for easier digestion and mixing Also commonly hydrolysed into collagen peptides Taste and texture Can have a mild marine taste if not well formulated Usually more neutral, though this depends on the product Dietary considerations Not suitable for fish allergies, vegans or vegetarians Not suitable for people avoiding beef, vegans or vegetarians Main thing to check Source, collagen dose, peptide format and taste Source, collagen dose, peptide format and quality Is marine collagen worth taking?  For most people interested in skin health, marine collagen is a reasonable, low-risk supplement to try, as long as your expectations are realistic. The evidence for gradual gains in skin hydration and elasticity is reasonably solid. The case for hair, nails and joints is softer, but it's building. It also works best as one piece of a bigger picture and should be consumed alongside a protein-rich, varied diet, decent sleep, sun protection and staying hydrated. If you do give it a go, choose a hydrolysed product with a sensible dose and supporting nutrients like vitamin C, commit to a consistent 8 to 12 weeks, and judge the results for yourself. Whatever source you land on, quality and consistency are what turn a supplement from a hopeful purchase into a habit worth keeping. That is the standard we hold every formula to at Innermost: science over hype, quality ingredients and nothing you do not need. Whether you are looking at collagen, protein or everyday wellness support, the same rule applies: choose what fits your body, your goals and the routine you can actually stick to. If you're not sure where to start, our free nutritionist consultation can help you work out what actually fits your goals. Frequently asked questions  Is marine collagen better than bovine collagen?  Neither is outright better. Marine is primarily Type I and may appeal to those looking for a fish-derived source, while bovine offers Types I and III and is often cheaper. Can vegans take marine collagen?  Marine collagen comes from fish, so it isn't suitable for vegans or vegetarians. Vegan "collagen support" products work differently, supplying nutrients such as vitamin C that contribute to normal collagen formation rather than collagen itself. Does marine collagen taste fishy?  A good-quality hydrolysed marine collagen should be virtually flavourless. A noticeable fishy taste is usually a sign of a lower-quality product. How much Marine Collagen should I take? Most research points to an effective daily intake of somewhere between 2.5g and 15g of collagen peptides, with many of the skin studies sitting in the middle of that range. References Czajka, A., Kania, E., Genovese, L., Corbo, A., Merone, G., Luci, C., Sibilla, S., Siciliano, C. (2018). Daily oral supplementation with collagen peptides combined with vitamins and other bioactive compounds improves skin elasticity and has a beneficial effect on joint and general wellbeing. Nutr Res. 57. Click here. Farooq, S., Ahmad, M., Zheng, S., Ali, U., Li, Y., Shixiu, C., Zhang, H. (2024). A review on marine collagen: sources, extraction methods, colloids properties, and food applications. Collagen Leather. 6(11). Click here. Myung, S., Kim, J., Lee, Y., Choi, Y. (2025). Effects of collagen supplements on skin aging. Am J Med. Click here. Pu, S., Huang, Y., Pu, C., Kang, Y., Hoang, K., Chen, K., Chen, C. (2023). Effects of oral collagen for skin anti-aging: a systematic review and meta-analysis. Nutrients. 15(9). Click here Evans, M., Lewis, E., Zakaria, N., Pelipyagina, T., Guthrie, N. (2021). A randomized, triple-blind, placebo-controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity. J Cosmet Dermatol. 20(3), 825–834. Click here. Hexsel, D., Zague, V., Schunck, M., Siega, C., Camozzato, F., Oesser, S. (2017). Oral supplementation with specific bioactive collagen peptides improves nail growth and reduces symptoms of brittle nails. J Cosmet Dermatol. 16(4), 520–526. Click here. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA). (2010). Scientific Opinion on the substantiation of health claims related to biotin. EFSA Journal. 8(10), 1728. Click here. Read more
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A few years ago, most of the questions I got as a coach were about the usual stuff: how to lose a bit of fat, how to add a bit of size, how to break a plateau. These days? A huge number of them involve a weekly injection. GLP-1 medications have gone from a diabetes treatment to a genuine phenomenon, and honestly, I get it. The results people are seeing can be seriously impressive. But here's the part that never makes it onto the before-and-after photos. When you lose weight quickly, not all of what disappears is fat. Some of it can be muscle. And muscle, I'd argue, is the very last thing you want to wave goodbye to. It's what keeps your metabolism ticking over, what keeps you strong and capable as you age, and a huge part of why some people end up looking lean and athletic while others just end up smaller and softer. I've spent more than 12 years in and around the gym, and the best part of a decade coaching people through exactly this kind of body composition change. So I want to be straight with you, because there's already a lot of noise around this topic. Some of it is scaremongering, some of it is wishful thinking, and a lot of it is people repeating things they've half-read somewhere. You won't find any of that here. Just a clear, honest look at what's actually going on, and what you can do about it. Stick with me. Key takeaways A GLP-1 can absolutely cost you some muscle, but the early panic massively oversold it. With the right approach, muscle loss is very manageable. The whole challenge comes down to one tension: these medications push your appetite down at the exact moment your protein needs go up. Resistance training is your single most powerful tool. If you take one thing from this article, let it be that. Prioritise protein, don't slash your calories to nothing, and stay on top of your hydration. Supplements won't do the work for you, but a good protein blend and creatine genuinely earn their place when your appetite has gone walkabout. This is a tool, not a shortcut. Pair it with proper training and nutrition and you can come out the other side leaner and stronger. First Though, What Is a GLP-1? Let's clear up the science, because once you understand it, everything else clicks. GLP-1 stands for glucagon-like peptide-1, and it's a hormone your own gut already releases after you eat. Its job is to tell your brain you've had enough, slow down how quickly your stomach empties, and help manage your blood sugar by prompting a well-timed insulin response. Think of it as part of your body's built-in "I'm full" system. The medications everyone's talking about are GLP-1 receptor agonists, which is just a fancy way of saying they mimic that hormone, only at a much bigger dose and for far longer than the version you make naturally. The result? Your appetite drops off a cliff. Food becomes less interesting, portions shrink, and the result is weight loss. The Most Common GLP-1 Medications There are quite a few GLP-1s that are widely available today. Here are ones you're most likely to come across in 2026: Semaglutide Sold as Ozempic (for type 2 diabetes), Wegovy (for weight loss), and now as an oral tablet too. This one is a pure GLP-1 agonist. Tirzepatide More often known by the names Mounjaro and Zepbound. This is a dual agonist: it works on GLP-1 receptors and a second pathway called GIP, which is part of why it tends to produce greater weight loss. Liraglutide An older, daily-injection option you may still come across under the names Saxenda, and Victoza.  Orforglipron One of the newer arrivals, and notable for being a GLP-1 you take as a pill rather than an injection. A note on retatrutide If you’ve any knowledge on GLP-1s already then you might also have heard the name retatrutide, and this one deserves an honest word. It's the furthest along of the next-generation of weight loss solutions: a triple agonist that adds genuine glucagon receptor activation into the mix (more on that in a second) and has posted the biggest weight loss numbers we've seen yet. The catch? It hasn’t been approved yet. The Phase 3 trials are still running as I write this. I'll be straight with you though: that hasn't stopped people getting hold of it. But unapproved means unregulated, which means there's no real way of knowing what's in an unofficial vial, or in what dose. That's a conversation for you and a doctor, not a shopping decision. I'd leave it well alone until it’s approved and available from a regulated, reputable manufacturer. A quick myth worth busting You'll often hear that GLP-1s "work on your glucagon receptors." Not quite, and this is worth getting right. Your standard GLP-1 medications actually reduce the release of glucagon (a hormone that raises blood sugar) as part of how they keep your levels steady. They don't switch the glucagon receptor on. The only drugs that deliberately do that are the new triple agonists like retatrutide, where that extra action is used to nudge up energy expenditure and fat burning. It's a small detail, I know, but it's exactly the kind of thing that separates good information from the stuff doing the rounds online. Do GLP-1 medications cost you muscle? The honest answer is they can, but the early panic about this massively oversold the reality. The far more useful question is what you can actually do about it, which turns out to be quite a lot. Here's what's going on. When you lose weight quick, whatever the method, a chunk of that loss tends to come from lean mass rather than fat. With GLP-1s, some studies suggested lean mass could account for a significant share of the total weight lost by those using them. Cue the "Ozempic is wasting your muscle" headlines. But the picture has matured a lot, and it's far less scary than it first looked. More recent research suggests a good portion of that "lean mass" figure isn't skeletal muscle at all. It's water, and it's changes in organs like the liver, which shrink as you get healthier. Several analyses now show that while you might lose some absolute muscle, your relative muscle (muscle as a proportion of your now-lighter body) and your strength can hold up or even improve. So no, this is not a reason to avoid these medications if they're right for you. It's simply a reason to be deliberate. Where I would be paying closer attention is with people who fall into the higher-risk groups: Older adults, who are already losing muscle gradually with age and really can't afford to speed that up. Anyone with low muscle mass from the outset of treatment. People losing weight very fast with no resistance training and not enough protein. If any of these sound like you, then everything below isn't optional. It's the whole point. The one thing that defines all of this Here's the tension at the heart of being on a GLP-1, and once you see it, the rest of this article basically writes itself. To protect and build muscle, your protein needs go up. But the medication's entire job is to send your appetite down. You need to eat more of the right stuff at exactly the moment food has become least appealing. That's the puzzle. So let's solve it. Make every bit of your nutrition count When you're barely hungry, you simply can't afford to waste your limited appetite on food that isn't doing much for you. Protein needs to become your priority, full stop. How much? The International Society of Sports Nutrition puts the sweet spot for active people at around 1.4–2.0g of protein per kilogram of bodyweight per day, with the higher end being useful during dieting phases. And make no mistake, being on a GLP-1 is very much a dieting phase. For an 80kg person, that's somewhere in the region of 130–160g a day. The trick is to spread it across your meals rather than backloading it all into dinner, because your muscles respond best to regular protein "doses" through the day when you’re in a calorie deficit. A few principles I give clients in this exact situation: Lead with protein When your appetite is small, eat the protein on your plate first, before you fill what little room you have with everything else. Sounds obvious. Hardly anyone does it. Don't crash your calories or be reckless I know it's tempting when you're just not hungry, but if your overall intake drops too low, you give your body every reason to break down muscle for fuel, and your training will fall apart. A controlled deficit beats a brutal one every single time. Stay on top of hydration and electrolytes GLP-1s can bring nausea and digestive upset, and anything that cuts how much you eat and drink can leave you short on fluids and salts. That flat, foggy, weak feeling people blame on the medication? Often it's just dehydration in disguise. Make a habit of drinking water regularly and add an electrolyte supplement if you’re still not feeling right. Training is crucial while on weight loss medication If I could give you only one instruction for your entire time on a GLP-1, it would be this: lift weights.  I genuinely can't stress this enough. As a qualified coach, I've watched resistance training do more to protect muscle during weight loss than anything else in the body transformation toolkit, and the science backs that up completely. A major 2025 advisory from several leading obesity and nutrition bodies landed on a clear recommendation for people on these medications: strength training at least three times a week, plus around 150 minutes of aerobic activity. That's a pretty basic formula but it works! Why does lifting matter so much? Because it sends your body a message. Cardio is brilliant for your heart and helps with the deficit, but it doesn't give your body any real reason to keep muscle. Lifting does. When you challenge a muscle, you're effectively telling your body, "I still need this, don't you dare get rid of it." And so, even in a calorie deficit, it holds on. Pretty clever, really. You don't need to live in the gym to make this work. You just need to train with intent: Build your sessions around the big compound movements (squats, hinges, presses, rows, and their machine equivalents) that recruit a lot of muscle fibres at once. Aim to do a little more over time, whether that's a touch more weight, an extra rep, or simply better control. This is progressive overload, and it's the engine behind keeping and building muscle. It's the closest thing to a non-negotiable there is. New to this, or coming back after a long time off? Start sensibly. Two or three focused sessions a week will beat an ambitious six-day plan you've quietly abandoned by the end of the month. Something is always better than nothing. Where supplements fit I'll always give it to you straight here, even when it's not the salesy thing to say: no supplement is going to rescue you from skipping the gym or neglecting your protein. The basics come first, second and third. There's no powder on earth that changes that. That said, supplements absolutely earn their place when they solve a real problem, and a GLP-1 hands you a very specific one. Remember the puzzle from earlier? High protein needs, tiny appetite. This is exactly where a good protein blend stops being a "nice to have" and becomes genuinely useful. Getting 30-odd grams of quality protein in a single shaker is a whole lot easier than staring down a plate of chicken and rice you don't have the appetite for. A few that fit the job: Whey protein Our The Strong Protein packs 34g of protein into one low-calorie serving, with 3g of creatine built in (more on why that matters in a second). If your main focus is staying lean through the deficit, our Lean Protein is built with exactly that in mind, and if you're plant-based, our Health Protein gives you a vegan option without dropping the quality. Creatine Creatine is one of the most researched supplements on the planet, and a genuine ally when you're dieting. It supports your strength and helps you maintain lean mass while you train. It's already in The Strong Protein, or you can top up with The Power Booster, which is pure creatine monohydrate. Take 5 grams daily without fail; the timing matters far less than the consistency. Hydration support Given the digestive side effects and the natural dip in how much you're eating and drinking, an electrolyte blend like our Hydrate Blend can be a real help, especially on training days. Everything we make at Innermost is built the same way: real, evidence-backed ingredients in doses that actually do something, with none of the filler or fairy dust. That matters more than ever when your appetite is limited, because every single serving has to pull its weight. If you want to see the full range, you can browse it all here. Your GLP-1 Muscle-Preservation Playbook If you skim everything else, don't skim this. Here's everything you need to know in 7 short points: Prioritise protein. Aim higher than feels natural, spread it across the day, and eat it first. Lift weights at least three times a week. Compound movements, gradually progressed. This is the big one. Keep some cardio in. Around 150 minutes a week, for your heart and your calorie deficit. Don't under-eat to extremes. A sensible deficit protects muscle. A savage one sacrifices it. Stay hydrated. Replace your fluids and electrolytes, especially if side effects hit. Use supplements to plug the gaps. A protein blend and creatine do real work when your appetite is low. Be patient. Body composition changes show up over months, not days. Trust the process. One last, important word These are powerful, prescription medications, and everyone responds to them a little differently. Nothing in this article is medical advice, and it's no substitute for the guidance of the doctor or prescriber looking after your treatment. If you've got questions about your medication, your dose, or anything that just doesn't feel right, please take those to them. They know your full picture in a way that an article never can. What I can tell you, hand on heart, is this: being on a GLP-1 does not have to mean losing your muscle along with the fat. Treat it as a tool, pair it with proper protein, real training and a bit of smart support, and it can be the thing that finally gets you to a leaner, stronger version of yourself. Not just a smaller number on the scale, but a body that works as well as it looks. Now that's a goal worth training for. Read more