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The Innermost Guide To Psychobiotics

23rd March 2023

23rd March 2023

By Vikki Rich

There’s a lot of talk at the moment about our gut health and for good reason.

If you’ve been scrolling through any form of social media – maybe you’ve even caught a few of those adverts about bacteria friendly yogurts – then you’ve probably heard of the benefits that a healthy gut can have on the body’s physical health.

New evidence however suggests you have an extra reason to value the bacteria living in your microbiome: if they’re happy, so are you! This is what scientists term as the gut-brain axis. Studies show that a healthy gut microbiome is fundamental in linking the emotional centres of the brain with peripheral intestinal functions - think of a moment when you’ve had butterflies and felt excited or nervous, that’s the gut-brain axis in action. 

With these new discoveries, scientists have developed an equally apt term for these mentally beneficial gut bacteria called psychobiotics. Psychobiotics refer to bacteria that positively influence the gut-brain axis by balancing out the microorganisms within the gut-microbiome. But just what are psychobiotics? How do psychobiotics work? Could they be used in the future to treat mental health conditions like depression and anxiety by targeting gut health?

What are psychobiotics?

The term ‘psychobiotics’ doesn’t refer to any specific bacterial discovery or naturalistic fallacy. Instead, it is an all-encompassing term relating to any probiotic or prebiotic microorganism that reacts with the bodies existing gut bacteria to confer mental health benefits through the gut-brain axis. When ingested in an optimal and individually tailored quantity, psychobiotics improve the body’s ability to communicate between the gut and the brain and subsequently offer a wide range of benefits relating to psychological wellbeing.

While the idea of using these psychobiotics to impact the gut microbiome and improve mental health might seem silly, the gut is actually responsible for a lot of brain chemical processes. It houses an estimated 70% of our brains eventual immune cells, in addition to around 95% of our total serotonin – the feel-good chemical in the brain. As shown in controlled studies, a healthy gut actually increases the amount of this chemical being communicated to the brain.

Not every pre and probiotic has the same impact on the gut microbiome however, meaning that not all are classed as a psychobiotics. It’s entirely dependent on the bacterial benefits towards an individual’s mental health. Psychobiotic bacteria also come in all shapes and sizes and studies have shown that they confer different benefits relative to individual mental illnesses. 

What can they treat?

While scientific research into the benefits of psychobiotics on the brain-gut axis is still very much in its infancy – at least when compared to more established mental wellness treatments – we already know so much about the microorganisms. This makes psychobiotics one of the most exciting and interesting medical wellness fields. While not a fully comprehensive list, here are a few key benefits of psychobiotics backed up by scientific studies: 

Depression is one of the most common mental health disorders with an estimated 1 in 6 impacted by the condition. Again, while the general understanding of depression is limited, researchers have begun to identify different neurotransmitters potentially responsible for the condition that are also produced by the gut microbe through different psychobiotics.

Our Innermost Digest Capsules for instance contain both probiotic macrospores and prebiotic acacia fibre. While the former improves absorption of nutrients and reduces inflammation, the latter builds a stronger and diverse microbiome. Essentially, they strengthen the gut-brain axis. Both of these psychobiotic examples have also been evidenced to reverse depression symptoms from those suffering from IBS.

Schizophrenia is also a complex and long-term mental health with surprisingly minimal comprehensive research. Like gut-based afflictions such as IBS, one consistent factor of schizophrenia is the influence of genetics upon the disease. This has led to further studies into role of the gut microbiome in schizophrenia, with it suggested that gastrointestinal inflammation plays a key role in the development of the disease due to the microbiome imbalance. This is something that psychobiotic examples like Bifidobacteria and Lactobacilli have been suggested to benefit through the production of GABA – this generates dopamine, the brains feel good chemical.

Anxiety disorders are complex and can be caused by numerous factors – both genetic and environmental. This has led to many studies attempting to determine the benefits that psychobiotics can have for anxiety. While much research is still emerging, current evidence suggests that the vague nerve, one of the key communication processes between the brain and intestines can offer relief from the flight or fight struggles of an anxiety attack when triggered.   

How to implement psychobiotics into your daily life

It’s true that the prospect of adding another caveat to your dietary intake can seem daunting, we have prepared a few simple and easy tricks below to make going about it a breeze.

Psychobiotic Diet

One tried and true method is to get the mental wealth good stuff into your day is to slowly add psychobiotic foods into your daily diet until it becomes second nature routine. Foods like Yogurt and drinks like Kefir are a particularly good choice as they’re perfect for any time of day. For anyone feeling like something a little different, international dishes like Sauerkraut in Germany and Tempeh in Japan are full to the brim with the healthy gut-brain bacterium. Consuming these psychobiotic foods also has the benefit of providing a whole host of other beneficial nutrients as well as just being delicious to boot.

Psychobiotic Supplements

If you’re finding that you don’t have time to search for the more nuanced probiotic foods, you might find it beneficial to try probiotic supplements like the Innermost digest capsules (wink wink) as these provide a much greater concentration of the good stuff when compared to food intake.

Like anything, we would always recommend that individuals get a mix of both into daily life to create the perfect balance of convenience, nutrient uptake, and psychobiotic benefit.

Psychobiotics going forward

While our understanding of the gut-brain axis and psychobiotics is still very much in its infancy, our scientific understanding of gut health has come along way. From what was before seen as a taboo talking point, many people – us included – now feel confident to add to the discussion and begin to make changes to diet, lifestyle, and sleep, with the aim of improving wellbeing by improving gut health.

Thanks to an increasing number of scientific studies, we can take away that the gut and mind are deeply connected and can be optimised through psychobiotics to improve mental wellbeing.

With all this said however mental health conditions are highly complex with a wide range of medications and therapies used as treatments. As such, it’s important to take psychobiotic supplements in conjunction with these other therapies to get the best outcome possible.

Here at Innermost, we are at the forefront of science led solutions to individual wellness. That’s why we offer only the best and means evaluated pro and prebiotic supplements to help improve gut-brain health and communication. Not sure where to start? Contact our team at Innermost today for individually tailored from our expert consultation.

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Creatine for women
The word ‘creatine’ might conjure up images of gym bros, but don’t fall into the trap of thinking it’s just for men. Creatine is one of the most widely researched supplements in the nutrition game, and one which can offer a host of benefits to many people.  Let’s dig into the topic of creatine for women – how it works, proven benefits, how it differs for women vs men, and how to start working it into your routine. What is creatine? To put it simply, creatine is a mineral our bodies naturally produce which helps to create Adenosine Triphosphate (ATP) – a very important energy-carrying molecule.  It has been extensively researched for its ability to help increase performance in high intensity exercise1, potentially leading to greater training results.  You can find out more in our complete guide to creatine.  Creatine for women: why interest is growing There are a lot of misconceptions around creatine – maybe you’ve heard it’s for ‘bulking’ or that it causes undesirable water retention. Either way, there have definitely been some ideas floating around which could understandably have put people off working it into their nutrition regime.  In reality, creatine can support performance, strength and recovery without changing your body composition in the way some might assume. It can be a great tool for not only strength training but also HIIT and functional fitness, as well as overall health and even ageing!1  With all this in mind and more research coming out all the time, it’s no surprise that interest is growing amongst women when it comes to making use of creatine.  Creatine for women vs men: is there a difference? Creatine works in the same biological way for both men and women, but there are some differences in terms of the results or impacts you may see.  In general, women tend to have significantly lower baseline creatine stores than men2, meaning creatine supplementation can be potentially even more beneficial for them. 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Innermost’s The Strong Protein is a super powerful protein blend with 34g protein and 3g of creatine in every serving – giving you everything you need for a properly fuelled, powerful workout.   So, it’s a very effective supplement and it’s very easy to take. What’s not to love? Creatine for women – easy and effective Creatine is well-researched, easy to use and it can be super effective. If you’re interested in improving your performance, recovery and strength, it’s almost a no-brainer. Make it a part of your daily wellness routine, stay consistent with it and see the results - we think you’ll like them.  References Kreider RB, Kalman DS, Antonio J, Ziegenfuss TN, Wildman R, Collins R, Candow DG, Kleiner SM, Almada AL, Lopez HL. International Society of Sports Nutrition position stand: safety and efficacy of creatine supplementation in exercise, sport, and medicine. J Int Soc Sports Nutr. 2017 Jun 13;14:18. doi: 10.1186/s12970-017-0173-z. PMID: 28615996; PMCID: PMC5469049. Click here.   Smith-Ryan AE, Cabre HE, Eckerson JM, Candow DG. Creatine Supplementation in Women's Health: A Lifespan Perspective. Nutrients. 2021 Mar 8;13(3):877. doi: 10.3390/nu13030877. PMID: 33800439; PMCID: PMC7998865. Click here.  Wohlgemuth KJ, Arieta LR, Brewer GJ, Hoselton AL, Gould LM, Smith-Ryan AE. Sex differences and considerations for female specific nutritional strategies: a narrative review. J Int Soc Sports Nutr. 2021 Apr 1;18(1):27. doi: 10.1186/s12970-021-00422-8. PMID: 33794937; PMCID: PMC8015182. Click here.  Saito S, Cao DY, Okuno A, Li X, Peng Z, Kelel M, Tsuji NM. Creatine supplementation enhances immunological function of neutrophils by increasing cellular adenosine triphosphate. Biosci Microbiota Food Health. 2022;41(4):185-194. doi: 10.12938/bmfh.2022-018. Epub 2022 Jun 17. PMID: 36258765; PMCID: PMC9533032. Click here.  Mohammad Ali Izadi, Farhad Daryanoosh, The effect of creatine supplementation on muscle protein synthesis in athletes: A review. Nutrition Clinique et Métabolisme,Volume 39, Issue 4, 2025, Pages 273-281, ISSN 0985-0562. Click here.  Powers ME, Arnold BL, Weltman AL, Perrin DH, Mistry D, Kahler DM, Kraemer W, Volek J. Creatine Supplementation Increases Total Body Water Without Altering Fluid Distribution. J Athl Train. 2003 Mar;38(1):44-50. PMID: 12937471; PMCID: PMC155510. Click here.  Avgerinos KI, Spyrou N, Bougioukas KI, Kapogiannis D. Effects of creatine supplementation on cognitive function of healthy individuals: A systematic review of randomized controlled trials. Exp Gerontol. 2018 Jul 15;108:166-173. doi: 10.1016/j.exger.2018.04.013. Epub 2018 Apr 25. PMID: 29704637; PMCID: PMC6093191. Click here. Read more
Halal Collagen Cover Image
Collagen has become a staple in many modern wellness routines, used to support everything from skin health to recovery and joint function. But as its popularity has grown, so too has the need for greater clarity around what’s in these products - and how they’re made. Case in point - halal collagen. Unlike other supplement ingredients, collagen is typically derived from animal sources. This makes its suitability under halal dietary guidelines less straightforward. Two collagen powders may look almost identical on the surface, yet differ significantly in how they are sourced, processed, and certified, meaning that one might be halal compliant and the other not so much. For anyone looking to incorporate collagen supplements into their routine, understanding these differences matters. This guide breaks down what exactly makes collagen halal and non halal, where confusion often comes in, and how to choose a supplement that aligns with both your values and your expectations for quality. What is halal collagen? Halal collagen refers to collagen that has been produced in accordance with Islamic dietary laws. While the term “halal” is often associated with food, the same principles apply to supplements, including collagen powders and capsules. In practice, this means that halal collagen must meet specific criteria across its entire lifecycle - not just in its final ingredient form. What makes collagen halal certified? Determining whether collagen is halal goes far beyond scanning an ingredient label. Collagen itself is most sourced from bovine (cow) or marine (fish) origins. Whether either is considered halal depends not only on the source, but on how it has been handled from extraction through to final production. Halal sourcing The sourcing of collagen is the first step to halal certification. Firstly, for a collagen product to be halal it must be sourced from a halal permissible animal such as cattle (bovine collagen) or fish (marine collagen). For bovine collagen, animals must be raised and slaughtered according to halal principles and Islamic rites collectively known as Zabiha. This includes: Invocation of Allah's name (Tasmiyyah) at the moment of slaughter. A swift cut to the throat to ensure humane treatment. Slaughtering conducted by a sane adult Muslim. The animal must also be healthy at the time of slaughter. Without the above considerations, collagen supplements cannot be considered permissible, regardless of quality. Halal processing Processing is the next critical factor in halal collagen certification. Collagen extraction often involves enzymes or chemical treatments to isolate and refine the protein. This hydrolysis process often uses enzymes to break down collagen into peptides. These enzymes must be plant-based (e.g., papain) or sourced from halal-certified animals; porcine-derived enzymes (like porcine trypsin) are forbidden. If any of these substances are derived from non-halal sources, the integrity of the product is compromised. Any solvents or processing aids used during extraction must also be free from ethanol or other non-halal alcohols. Halal collagen certification also ensures that no prohibited additives, such as non-halal gelatine carriers or animal-based anti-caking agents, were introduced during the manufacturing process. Halal Manufacturing Manufacturing standards are also highly important in making collagen supplements halal certified. Even when ingredients are halal, shared facilities or inadequate controls can introduce cross-contamination. As such, the manufacturing of halal collagen must follow the below guidelines: Non cross contamination: certified products are produced under strict conditions that ensure separation from non-halal substances throughout production, storage, and packaging. Complete surface cleaning: If a facility handles both Halal and non-Halal products, a rigorous, religiously supervised deep cleaning (often called Samak or Taharah) must occur between runs. Auditors must verify that no "Najis" (unclean/prohibited) residues remain. Common Misconceptions About Halal Collagen As collagen has become more widely used, a number of assumptions have emerged around its suitability within a halal diet. These are some of the most common. Collagen is Halal be default: because collagen is a natural protein, it’s easy to assume it meets dietary requirements. In reality, its origin and processing determine whether it is permissible. Marine collagen is always halal: While often suitable, this still depends on how the collagen is produced and whether non-halal substances are introduced during processing. Hydrolysed collagen is always halal: As with other forms of collagen, halal permissibility depends entirely on its source and production. There is also a tendency to equate “clean” or “natural” products with halal compliance. While these qualities can overlap, they are not the same. A supplement may be free from additives and still not meet halal standards. Benefits of halal collagen When halal collagen is produced with quality and integrity in mind, it can support a range of wellness goals. While we’ve spoken about these before, however below are some of the key benefits of halal collagen: It plays a role in maintaining skin structure and elasticity. Supports joint function and contributes to recovery following physical activity. They form part of a broader approach to looking, feeling, and performing at their best. These benefits are closely linked to how the collagen is sourced and formulated. Products that prioritise transparency, clean processing, and effective formats - such as hydrolysed collagen peptides - are more likely to deliver consistent results. For those seeking halal collagen supplements, this alignment between quality and compliance becomes key. How to choose a halal collagen supplement? Choosing a halal collagen powder or supplement should feel straightforward, but in practice it often requires a closer look. Below are some of the key things you should look for when purchasing halal collagen supplements: Certification is the most reliable starting point. A recognised halal certification confirms that the product has been assessed across sourcing, processing, and manufacturing. Clear information about where the collagen is sourced and how it is produced can indicate a more considered approach to formulation. The type of collagen also matters. Hydrolysed collagen peptides are widely used because they integrate easily into daily routines and are readily utilised by the body. The overall experience of the product. Taste, mixability, and ease of use all contribute to whether a supplement becomes part of a consistent routine - which is ultimately where results are seen. Is Innermost halal? In short, yes. Innermost products are halal certified, meaning they meet strict standards across sourcing, processing, and production. This ensures that every stage of development aligns with halal requirements. Innermost’s The Glow Blend contains high quality halal certified hydrolysed bovine collagen peptides and is formulated to support your skin and overall wellbeing, with extra nutrients like hyaluronic acid, vitamin C, biotin and folate. Alongside certification, our Innermost proteins and supplements focuses on clean, effective formulations designed to support real results. We prioritise ingredient quality, avoid unnecessary additives, and create products that fit seamlessly into everyday routines. If you’re looking for a collagen supplement that aligns with both your nutritional goals and your values, explore the Innermost range to find a halal-certified option that fits seamlessly into your routine. References Permadi, S., Ujilestari, T., Hakim, L et al. Characteristics and Applications of Collagen from the Animal By-Product as a Potential Source for Food Ingredients. Permadi et al. Reviews in Agricultural Science. 2024, 327-346. Click here. Aslan., H. The influence of halal awareness, halal certificate, subjective norms, perceived behavioral control, attitude and trust on purchase intention of culinary products among Muslim costumers in Turkey. International Journal of Gastronomy and Food Science. 2023. Click here. Schmidt, M. M. et al. Collagen extraction process. International Food Research Journal. 2016. Click here. Read more